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Themed collection Coronavirus articles - free to access collection

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Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

单词invigorate 联想记忆:
Well, that’s it, kids: we’re heading home. Chinese shares are down 7 per cent, and thanks to the newly-instituted market circuit breakers, that means the market shuts.

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

卓越雇主排名:61
如果反弹幅度小、时间短,那么显然结构性变化已经开始了。我希望,过多投资于大成本项目的公司以及仍然高度依赖于油气收入的国家对此做好了准备。

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

Open Access Perspective

Soft matter science and the COVID-19 pandemic

Margot Wallstrom

Graphical abstract: Soft matter science and the COVID-19 pandemic
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

Banks, asset managers and insurance companies have flocked from mainland China to acquire prime Hong Kong office buildings, prompting the territory’s government to announce it will release more land for commercial redevelopment in the oversubscribed heart of the city.

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

Comic skit “Happiness Of Today II” (Shen Teng, Ma Li etc)
研究人员写到,对于1700年前的中国朝代来说,如果能征服并有效的管理龟兹的话,那么他们就能够控制住西域所有的绿洲城邦。
The worst of 2015
“你美丽得如此不真实,我的视线无法从你身上移开”,这爱意满满的歌声使金发女郎笑得合不拢嘴,同时她也拿出手机记录下了这美妙的一刻。

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

《琅琊榜》的意外爆红让这部戏成为2015年秋季档电视剧中的翘楚。同样改编自网络小说(海晏著)的《琅琊榜》2015年9月首播。该剧由胡歌、刘涛等人主演,讲诉了才冠绝伦的谋士梅长苏为昭雪多年冤案进行的一系列斗争。虚构的人物和朝代让改编剧集巧妙地躲过了历史准确性上的责难。它精美的场景布置和无懈可击的故事情节受到了广大观众的一致好评。
Chinese Premier Li Keqiang said the economy performed better than forecast in 2017 and expects annual gross domestic product growth of around 6.9 per cent, according to state media.
Those with 3-years of driving experience and no records of traffic accident crimes, dangerous driving, drugs or drink driving will be allowed to take examinations for online-driving services.
“An interviewer walked inta closet instead of the meeting room.”

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

综合考虑,这些事实与战略规划凸显了中国航天工业的认知——为了成为有竞争力的全球飞机制造商,中国需要拓宽行业的广度与深度。在他们掌握了价值链的两端——飞机设计与集成组装后,中国意识到长期处于价值链中游的组装和子系统地位将摧毁他们的航空业。这就是为什么中国雄心勃勃地与波音、空客等飞机制造商以及美国通用电气公司、劳斯莱斯等发动制造商竞争,形式前所未有地激烈。

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

adj. 突出的,显著的,未支付的

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

海莉·威廉姆斯依然是颇有影响力的重要存在,一位不论是低声哼唱还是大声呐喊都能令人信服的歌手。她直言不讳的勇气几乎使你忘记《欢笑过后》记录的是她对这个世界的厌倦。
Not because I am happy to see the end of what was one of television’s smartest series, a pioneer of what is now generally accepted as the current golden age of small-screen serials.

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
From the themed collection: 沪指涨0.88% 报3054.25点 成交3828亿元
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

The cemetery was first found in July 2007and was excavated by the Xinjiang Institute of Cultural Relics and Archaeology,with assistance from local authorities. The research team, led by Zhiyong Yu,director of the Xinjiang Archaeological Institute, published the findings in Chinese in the journal Wenwu. The article was recently translated into Englishand published in the journal Chinese Cultural Relics.
《琅琊榜》

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
From the themed collection: 楼市调控不放松 热门城市渐冷静
Open Access Review Article

Diagnostic technologies for COVID-19: a review

8、《自杀小队》
Weaker demand from emerging markets made 2015 the worst year for world trade since the aftermath of the global financial crisis, highlighting rising fears about the health of the global economy.

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

The report by iResearch Consulting Group and Sina Weibo, China's most popular microblogging platform, was released at a forum in Shanghai, co-organized by Weibo and telecom giant Huawei .
The CHIP, which retails for $150, can only bake four full-sized cookies at a time. If you were go the traditional way and bake a large batch in the oven, you'd have anywhere between eight and 12 cookies in under 30 minutes — and it's also cheaper.
音乐界收入最高的女明星,她一直以来的赚钱方式是靠大量的世界巡回演唱会,持续不断的热门单曲和一系列主流公司的代言,而且很少露骨地讽刺她的主要竞争对手。
We will endeavor to transform and upgrade traditional industries.

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

本次问卷调查的主要对象为中国高校2017年应届毕业生,包括大专、本科、硕士及博士等,智联招聘最终收回有效样本93420份。

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

“今年榜单有趣的地方之一是,尽管网站都开始实行更严的密码设定政策,位数少的密码仍出现在今年的榜单上。”
民粹主义的兴起(即使在美国和英国这样的就业人数众多的国家也是如此)使得政客们认识到,就业的质量和数量同等重要。

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

Life Is Strange

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

汉娜库赫勒(Hannah Kuchler)是驻旧金山记者

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

Here is my best guess - and that's all it is - for how the U.S. economy and markets will look in 2010:
圣加伦大学其他单项高分包括在校友国际流动性方面排名第一,在国际体验方面屈居亚军,在就业安置方面排名第三。
这两个非比寻常的性玩具将在美国旧金山亚洲艺术博物馆即将举办的展览中展出。
该银行预测,寻找对冲通胀的方式的指数基金(那些追踪大宗商品指数的基金),将在明年下半年回归农产品市场。

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

会。梅因为失算的提前选举而失去了大部分权威。但过去几个月情况对她较为有利。敲定退欧离婚协议,确保了她的饭碗短期无忧。因此直到2019年英国退欧正式完成(或者另一种更吸引人的替代方案出现)前,保守党将让她继续坐在首相位置上。留欧派和退欧派都希望避免因反对她而引发内战。事实将证明,曾经被人们认为是坐不长的位置,意外地能够坐久。
《大城小妞》(Broad City),Comedy Central,1月14日播出。伊拉纳·格雷泽(Ilana Glazer)与艾比·雅克布逊(Abbi Jacobson)带着第二季回归了,它讽刺了纽约那些大材小用而又自恋的人们生活中的故作姿态、妥协与纯粹粗俗。
Matt Damon was named best actor in a comedy or musical motion picture for his role as a stranded astronaut in The Martian.
南韩的活动分子在星期二发誓,要在月底通过宣传气球跨越边境向北韩偷运荷里活讽刺片"刺杀金正恩",以作为对北韩不断威胁的反抗。
走上一段旋转楼梯就是几间卧室。中间有一处阁楼式的书房俯瞰着中庭。主卧套间和配套的浴室内有几面玻璃墙可以观赏数英亩湿地的景色。这个套间通往该房屋临水一侧的一个阳光平台。另外两间卧室也带有配套的浴室。底层已全部装修,用作健身房,并带有一间无洗浴功能的卫生间和一间可停放几辆车的车库。

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
From the themed collection: 弹性建筑涂料更受消费者青睐
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

小贝现身纽约时装周 为凯特选嫁衣?
Third, McDermott provides some protection against the possibility of Andre Roberson departing as a free agent in the summer.

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
From the themed collection: 广东:新增绿色建筑9335万平方米
Critical Review

The role of biosensors in the detection of emerging infectious diseases

你感到抓狂是对的。公司无时无刻不在监视着你。无论你做什么都有记录:你打的每个电话,发的每条短信,每条在推特上发的帖子和讯息。在大部分公司,这些记录可永远不会删除(这吓人的吧,真可怕~)

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

Dachis says: The news just keeps getting worse for Mitsubishi. Low sales triggered a decision to pull out of the European market and if the levels of negative discussion are any indicator, 2013 doesn’t look to be any better.

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

清华大学和北京大学分别排在第14位和第17位,与它们去年各自的排名相同。
1.无论在什么情况下都不要问出租车司机,对于今年夏天伦敦的奥运会有多么激动。不是说他会勉强或尴尬地发表个人意见,而是你根本就不该问这个问题。
But national and racial identity were often conflated for the white majority. That identity felt to many white people like one of the most important pillars holding up their world — and now it seems under threat.
Over 90 percent of them attended schools in English-speaking countries, such as the US, the UK and Australia, and over 70 percent pursue at least a bachelor's degree, according to the MOE.

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

Jennifer Lawrence also took home the gong for best actress in a movie for her role in the critical darling Joy.
拯救非洲癌症患者
The predictions of no further action in an annual Financial Times poll of eurozone analysts came despite Mr Draghi’s attempts to convince markets that the ECB remained primed to act should inflation and growth across the single currency area continue to disappoint.
欧洲工商管理学院(Insead)领衔2017年英国《金融时报》全球MBA百强榜。这是这所拥有多个校区的国际商学院连续第二年高居榜首,去年该学院首次摘得桂冠。

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

1. Jennifer Lawrence
相比之下,巴西雷亚尔升值促使咖啡和糖价格飙升,因为该国是这两种商品的最大生产国。

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

3.会飞的自行车
9. The 2012 Ig Nobel Anatomy Prize
莱蒂齐娅·巴塔利亚按时间顺序为当地一家报纸记录了七八十年代巴勒莫的黑手党战争。如今,她的照片被一些博物馆和回顾展收录。
4. 2012年搞笑诺贝尔奖之神经科学奖
虽然周六欧锦赛中爱尔兰0-3不敌比利时,但这并没有让赴波尔多看球的爱尔兰球迷一蹶不振。

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

我立刻赞同了克雷格和尼尔关于艾伦是今年颁奖礼最合适的主持的想法。我们希望举办一场娱乐、吸引人而又有趣的颁奖礼。
Despite the reported success of the Duke and Duchess of Cambridge's official visit to Canada back in September, timekeeping needs to be looked at for future trips.
Global smartphone shipments reached 1.47 billion units in 2016, up by 2.3 percent from last year, said IDC.

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

“What Happened, Miss Simone?” (Liz Garbus)
adj. 毁灭性的,令人震惊的,强有力的

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

The biggest story of the festival had nothing to do with films. It was about shoes. On Tuesday trade magazine Screen reported that a group of women had been denied access to a screening of Todd Haynes' Carol because their footwear – flat shoes with rhinestones – was unsuitable for the red carpet. Further tales came tumbling forth, social media erupted in indignation and soon enough we were soon dealing with a fully fledgedscandale. The Cannes press office rushed out a garbled statement: “Rules have not changed throughout the years (Tuxedo, formal dress for Gala screenings) and there is no specific mention about the height of the women's heels as well as for men's. Thus, in order to make sure that this rule is respected, the festival's hosts and hostesses were reminded of it.” Well, that cleared that up. Perhaps wisely, press screenings are exempt from any dress code: scruffy journalists are free to ascend the Palais' steps in flip flops and trainers.
16. Most Ignored Truism “There’s a myth in the business that young males drive the box office,” Tom Rothman, the chairman of Sony Pictures Entertainment’s motion picture group, told The Hollywood Reporter in November. In this same interview, Alan F. Horn, the chairman of the Walt Disney Studios, tried to make it simple: “There are variables that do affect what one pays any performer. Angelina Jolie, for example, got a lot more money for ‘Maleficent’ than Daisy Ridley did for ‘Star Wars,’ but they’re both women.” (Gee, thanks, Alan!)
学员平均年龄:36岁

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

SplashData的首席执行官摩根·斯兰说:“当你看到‘最差劲密码’榜单上出现‘adobe123’或者‘photoshop’,你就该意识到,在你正在使用的网站或应用上,不该用它本身的名字作为密码。”
In August, the holdings were to the tune of $80.4 billion while it stood at $79.7 billion in July.
整形美容长期以来一直在美国盛行,而如今这个潮流正席卷亚洲。

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

From the themed collection: 建立大湾区 绿色发展协调机制
Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

vt. 作 ... 姿

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

She had recently emerged as the right hand of her father, the former Prime Minister Nawaz Sharif. But corruption charges are clouding her rapid rise.

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

在“有工作经验要求”项目排行榜上,伦敦商学院的学生在毕业3年后平均薪资最高,为13万美元左右,目标实现率也最高(87%)。该项目还在就业成功率以及国际课程经验方面拔得头筹。该学院学生在国际流动性和职业进展方面排名第二。
[k?ut?]

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

After 'Gravity' and 'American Hustle,' my picks are in alphabetical order:
Song “The Spring Blossom” (Na Ying)
Every point we think we've reached where James cannot be better than he has been, he then blows past it like a poor center switched onto him. What will be discussed most is his all-encompassing skill, but this is also a testament to the work that James puts in. You can mock all those Instagram videos he puts up, but those are the real reason he's still able to do this; James has never cheated the game, not a day in his life, and the result is incomparable performance night in and night out.
保险代理人员也增加了93.62万人,总人数逾560万人。

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

2. Audiologist
What dangers does the Fed present to EMs today? One of the biggest risks, says Mr Koepke, is that it might “get behind the curve” and delay raising rates for too long. This would result not only in a surprisingly big hike when it came, but also a higher terminal interest rate than would otherwise be the case.

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
From the themed collection: 家居消费更倾向于大卖场
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

Every four years, Allianz holds an international Olympics for its sports teams. The company covers the athletes' expenses and has an opening ceremony; in 2010, the games were held in Budapest with over 70 countries participating.
He also has serious thrill issues dude.

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

vi. 流通,循环,传播

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

在以结束迫害科索沃境内阿尔巴尼亚族为目的和平谈判破裂后,北约于1999年3月24日开始了轰炸行动。南斯拉夫和科索沃境内的目标均受到了打击,首先是对抗北约战机的塞尔维亚防空网络,接下来是一系列范围更大的目标,包括被指直接参与迫害科索沃人的南斯拉夫军事力量。目标清单中还包括南斯拉夫首都贝尔格莱德境内的政治和军事目标。
《患难与共》(Togetherness),HBO,1月11日播出。HBO台的周日晚间喜剧组合中已经有了20出头的纽约女人(《都市女孩》[Girls]第四季第一集将在同一天晚上播出),还有快到30岁的旧金山男同性恋(《寻》[Looking]也在当天开播第二季)。现在又来了30多岁的洛杉矶异性恋者们。这部有点阴郁的半小时喜剧来自杰伊(Jay)和马克·杜普拉斯(Mark Duplass),兄弟俩曾经合拍过《肥大的椅子》(The Puffy Chair)和《纸袋头》(Baghead)等诡异的电影。马克·杜普拉斯和梅兰妮·林斯基(Melanie Lynskey)饰演一对夫妻,和杜普拉斯最好的朋友(史蒂夫·齐西斯[Steve Zissis]饰演)与林斯基的姊妹(阿曼达·皮特[Amanda Peet]饰)合住一栋房子。
每平方英尺单价:395美元(每平方米约合人民币2.7万元)
The January-to-November period in the United States this year was the warmest first 11 months of any year on record for the contiguous states. And 2012 will likely surpass 1998 as the warmest year on record for the nation, according to the National Oceanic and Atmospheric Administration.

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

7、 阿斯顿·马丁必须有。不止如此,还要在异国情调的赌场里挥金如土——一掷千金的男人很能吸引寻欢中的女性。常与女性周旋的邦德更擅长于此。
据悉,大多数借款的女性年龄都在19到23岁之间。

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

《哈利·波特》粉们,福利来啦!该片是《哈利·波特》前传,讲述了纽特·斯卡曼德在老纽约的冒险经历。该片根据《哈利·波特》中霍格沃兹学院的同名教科书改编而成。
单词haven 联想记忆:
祝福您,新年快乐。

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

n. (准备好演出的)节目,保留剧目,(计算机的)指令表
Unfortunately for May, the big drop in the pound since the Brexit vote means her salary has plunged in dollar terms.
一些最近发表的科学论文说,高空急流中这种持续较长的怪现象,由于全球变暖正在导致北极地区海洋中的冰迅速融化而变得更可能发生,但许多主要的科学家还没有被这种观点说服。

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

US listings were up from 2016, which marked the one of the weakest periods in years. According to Dealogic, 112 IPOs have priced year to date, versus just 63 at this time last year. Issuance volume has more than doubled to $31.6bn.
税:2014年约为16866美元(约合人民币10.8万元)

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

马特·达蒙凭借他在《火星救援》中扮演的被困宇航员一角而荣获喜剧类最佳男主角奖项。
受到密切关注的财新(Caixin)采购经理人指数(PMI)系列调查显示,该指数在四个月来首次显示扩张趋势。这一结果表明,上个月中国经济活动出现了增长。
['k?pirait]

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

The drama got 7.2 points on Douban, receiving criticism for having too much romance and too few of Zhou's struggles.
初创公司

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

节目29 创意乐舞《指尖与足尖》,郎朗 侯宏澜
时间:2010-05-31 编辑:francie
7、人民币贬值

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
From the themed collection: 温州万全将建国际家居直销中心
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

4. 西班牙企业学院

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

社交名媛卡戴珊8月份参加凯莉·詹娜的19岁生日聚会时,笨手笨脚从跑车出来的方式让她不小心走光太多了。
2.You Never Have a Day When You Wake Up Excited To Go To Work

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

凯莎《彩虹》
9. How to reset iPod

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

Sam Smith is a fluid soul man, with style channeling Otis Redding, Aretha Franklin and Ray Charles alongside modern icons like Amy Winehouse and Adele.
"过去,大熊猫很难进行圈养,但是经过成都熊猫基地和世界各地许多动物园的通力合作,人类已经攻克了这个难题。目前世界上已经有了将近400只人工大熊猫。" 马文如是说。

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

?奥巴马总统在纽约和新泽西宣布一场“大灾难”。洪水摧毁了海岸和超过230万人失去了电。在新泽西国家警卫队从洪水中救出数百人。州长克里斯?克里斯蒂,共和党人,说这次损失是“无法想象的”。他赞扬了从奥巴马那收到的“突出”配合。
单词toxic 联想记忆:

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

6. 2012年搞笑诺贝尔奖之文学奖

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
From the themed collection: 建筑用非织造材料更新的超前考量
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

Analysts survey by Bloomberg expected a rise to 1.9 per cent in January.
The unemployment rate probably won't fall quite as rapidly in 2015, according to economists, especially if more people enter the labor force because jobs are easier to find. Yet another large spate of hiring similar to the gain in 2014 would make the low unemployment rate more believable.
We'll start our review with the South American nations, and who else could we begin with, but the hosts Brazil. Rewind 18 months and they looked like they'd be struggling, but the appointment of 'Big Phil' Scolari has been inspired, and he's brought a belief to the team that was previously missing. Last years 3:0 demolition of Spain in the Confederations Cup final shocked many experts, and all of a sudden the Brazilians have expectations on them. Whilst you can't argue with that scoreline, we still wonder if Brazil have the firepower to win such a long tournament. Neymar is expected to conjure up the magic, but they're relying on Fred to come up with the goals. No disrepect to Fred, but the last two Brazilian teams to win the World Cup, in 2002 and 1994, could count on the likes of Ronaldo and Romario to lead the front line, two genuine legends of the game.
发展最迅速的初创公司往往具有全球化的视野。未来一年,美国总统特朗普已经实施的移民限制,以及英国作为退欧的一部分而在考虑的限制措施,可能会对企业招聘形成障碍。

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
From the themed collection: 租房“坑”多 小心中招
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

The University of St Gallen’s domination of the Financial Times’ ranking of masters in management courses continues for another year.

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

"He was not on the intelligence services' radar," added the prime minister.
de去掉,but。去掉but?导演Z(平静):你可以上台了。女演员F:but我还没准备好呢?Z(有点儿烦):哪那么多事儿呀,快点儿!F:but我这可是第一次!Z(强忍):谁没有第一次呀,快!F:but…,Z(已经怒了):哪XX那么多but呀,全都给我de掉,再不上去我就X人了!!!
It pours the perfect pint from the bottom of the glass.

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

The thing about the Mavericks is that this is not at all how Dirk should go out. That team has been so solid his entire career. To have a busted season now is painful. Maybe he ought to have joined Kobe, KG, and Big Fundamental last summer.
original

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

For now, occasional high-ticket deals such as the Dah Sing Financial Centre and the purchase of a HK$2.1bn luxury house on the affluent Peak, come amid wider pessimism about the sector. The office sector showed the most activity in the first quarter this year, but this still translated into only eight deals in total, according to CBRE.
Premiered in August, the 48-episode TV series is a fictional story, with a plot centering on struggles and romance during the Qin Dynasty (221-206 BC).

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

[di'pɑ:t]

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
From the themed collection: 央行:去年个人房贷增速明显回落
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

The book reflects growing anxiety in some quarters about the possible negative impact of automation on jobs, from manufacturing to professional services. The subtitle of its UK edition warns of “the threat of mass unemployment” and, in the US edition, foresees “a jobless future”.
Sohmers表示:“我曾经先后三次申请加入麻省理工学院研究室。我第一次申请的时候是14岁,那时我的父母并不太支持我。但是后来他们发现我在高中里学习并不快乐。于是他们开始慢慢理解了我的想法。现在他们对我的工作非常支持。”在加入麻省理工学院研究室之后,Sohmers终于找到了属于自己的天地。如今已经17岁的Sohmers表示,自己并不后悔放弃学业,进行创业。他表示:“即使我无法改变世界,也会收获一些其他的东西。人们在讨论上学和创业的时候,总是顾虑太多。但是企业是在研究者眼中,你的学历高低并不重要,重要的是你的能力。”
So take a look. I sincerely hope you enjoy reading them as much as I liked selecting and editing them.

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

“What Happened, Miss Simone?” (Liz Garbus)
Canada, the second largest country in the world in terms of landmass, ranks No. 2 overall. It takes top spots in Quality of Life and Best Countries for Education.
[.tr?nsp?'tein]
“我们一直用很高的标准要求自己”,库里赛后表示。“我们在第三节没有给他们防守端施加压力,草率地结束了我们的进攻并且给了他们机会。有很多需要我们继续提高的地方,当然,每个人都愿意在赢球的同时接受教训。”

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

Here are the 10 winners of the 2012 Ig Nobel Prizes given to scientists, writers, and peacemakers who make silly but thoughtful contributions to the world, or as the Annals of Improbable Research puts it, "first make people laugh, and then make them think." I can vouch for them making us laugh!
Hidrate Spark 2会通过移动App跟踪你的水摄入量和记录你一天喝了多少盎司的水,还可以根据在有盎司数标识的水瓶里灌了几次水来跟踪你的饮水量。

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

《华胥引》的故事是这样的:卫国公主以身殉国,不久死而复生,从此她改名换姓开始了新的旅程。电视剧改编自唐七公子的同名网络小说,于2015年七月首播,主演林源、郑嘉颖。不过和同类剧集相比,《华胥引》的人气就没那么高了。据网上的评论说,这部戏的主角和服装都不够抓眼。
The U.S. Congress and the media will go berserk when Goldman announces the size of its 2009 bonus pool. But the outrage will be brief and of little lasting consequence. The 'hate Goldman Sachs' story has been running just too long.
中国国家旅游局周五发出通知,确认了最近几个月中国游客因所持旅游文件不完整而被拒进入韩国济州岛的报道。该机构提醒中国公民“慎重选择旅游目的地”。

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
156 items - Showing page 1 of 3

About this collection

The story of the strong V-shaped recovery of the Chinese economy this year was followed by reports of soaring housing prices in many cities.
当我想要对一个机会大声喊“No”时,这往往是个信号,提醒我还有一个答案或许该是“Yes”。如此一来,我会深呼吸一下,然后尽量客观地分析现状。

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