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Themed collection Coronavirus articles - free to access collection

156 items - Showing page 1 of 3
Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

Do your homework. Read the assigned pages, and then some. Plug your topic into the Internet, grab another book at the library, and see what else you can learn about the subject.
东京大学(全球排名22名)和京都大学(35名)仍然是亚洲最顶尖的两所高校。

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

10月,政府宣布准备终结数十年之久的“独生子女政策”。此项政策限制了已婚夫妇的孩子人数。新规定要到明年才会生效。
slice

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

From the themed collection: 卫浴洁具行业的发展趋势与机会
Open Access Perspective

Soft matter science and the COVID-19 pandemic

单词debut 联想记忆:

Graphical abstract: Soft matter science and the COVID-19 pandemic
From the themed collection: 2015年1-11月顺德家具出口达69.8亿元
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

你倾向于隐藏自己的感情吗?

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

Haub School of Business at Saint Joseph’s University in Pennsylvania is the only school ranked for the first time, in 98th place.
2012年中国网游市场将占全球半壁江山
4. Precious metals: 'Going dark! Economic cycles point downward'
包括AT&T、IBM、西门子和施乐等在内的27家公司今年未能继续上榜。

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

凸起那部分有个“涡卷饰品”——(古埃及碑上)在王和神的名字周围的椭圆形装饰。考古学家在上面发现有眼镜蛇一只眼的符号。
We will endeavor to transform and upgrade traditional industries.
招聘经理看错了简历。
The dollar value of outbound shipments from China rose 12.3 per cent year on year in November, lifting from a revised pace of 6.8 per cent in October, and smashing a median forecast of 5 per cent from economists polled by Reuters.

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

[smɑ:t]

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

鉴于《速度与激情7》定于2014年夏季在各大院线上映,“巨石强森”将再次迎来丰硕的一年。凭借影片《海格力斯》(Hercules)他还可以做得更好。该片讲述的是这位神话英雄在完成其著名的12件苦差后的生活,极有可能拍摄续集。如果该部影片也能取得巨大成功,那么约翰逊在2014年将获得丰厚的票房收入。

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
From the themed collection: 北京南苑集体土地租赁房今天开工
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

Recipient: Their Royal Highnesses The Duke and Duchess of Cambridge (joint winners)
Trium is ranked first for the work experience of its alumni before the programme, second for aims achieved and third for international course experience. The programme is second for average salary ($307,003) of alumni three years after graduation, just behind the Kellogg/HKUST programme.

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

当你和他/她在一起的时候,你看不见周围的所有人,你的眼中只有他/她
‘The Good Wife’ Once Will (Josh Charles), Alicia’s illicit love interest, died at the end of Season 5, this sexy CBS courtroom drama seemed as if it might droop and wither, but instead, the sixth season steamed with almost madcap energy, mixing Alicia’s newly fledged political campaign, a war of the roses between Alicia’s new firm and her old one, and the legal travails of Cary, her legal partner. Alicia isn’t quite so good anymore, and that makes “The Good Wife” all the better.

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

如果说2017年是政策制定者们开始担心“无保障无产阶级”(precariat)人数增长的一年,那么2018年将是他们尝试为此做些什么的一年。
Against: It might be that bit too far from the mainstream to make a huge awards impact.

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

Cheryl Boone Isaacs, Academy President
摩根大通公司下滑至第4名,其总综合得分位居中国农业银行之后。去年名列前10强的两家欧企——荷兰皇家壳牌和汇丰控股,今年仅分别排名11名和14名。
To make a long story short, the Seppenwolde group went bankrupt shortly after Christmas of 1772. The disaster was a top story in Dutch newspapers. It ruined some of Amsterdam’s merchants and bankers. To prevent a general credit collapse, the city of Amsterdam stepped in temporarily as a lender of last resort. Sound familiar?
不会。随着美联储收紧货币政策并扩大美国与日本的利率差,2018年日本央行的日子会更不好过。但是日本央行行长黑田东彦(Haruhiko Kuroda)已决心只会因一件事而上调利率,那就是通胀。如果通胀开始加速,日本央行可能会让收益率曲线略微上扬,但到2018年年底时日本实际利率不会高于年初时的水平。

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

2017年我国继续同步提高企业和机关事业单位退休人员的基本养老金水平,惠及1亿多人。

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

The first view is that the price is inherently cyclical. What has come down must go back up again and the deeper the trough the higher the next mountain.
During the summers, Good Humor ice cream trucks visit the company's campuses every other Friday during lunchtime. In the fall, cider and doughnuts are served twice a month, mid-morning.

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

['?nim'pl?im?nt]

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
From the themed collection: 文化价值引领实木家具消费热潮
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

新生们对此事各持己见,《哈佛深红报》报道了一些学生的观点。其中有两位新生称取消这些人的入学资格是正确的。一名学生表示,“我不知道他们对这些冒犯无礼的图片有什么可辩解的”。

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
From the themed collection: 集成定制 改写未来家居
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

“New Yorkers have been waking up and realizing this long period of prosperity has wreaked a little bit of havoc on things that we think of as classic New York,” said Simeon Bankoff, the executive director of the Historic Districts Council, noting that 2015 will mark the 50th anniversary of the New York City landmarks preservation law. “Things we always thought were going to be there are just closing left and right.”
8. Smile every time EXCEPT when my team is losing.
Song “Fire In The Winter”(Kenji Wu and Dream Chorus)
泰勒·斯威夫特《名誉》

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

We will step up the development of public facilities in rural areas.
在美国股市整体被“踩下刹车”的情况下,特斯拉的股价还在一路狂飙。自今年年初至今,其股价已经上涨了80%,目前每股约262美元,接近该公司有史以来的最高值,市值达到320亿美元。
这是最好的时代,这是最坏的时代……
press挤压+ure→压力
Foreign investment in emerging markets has dropped to the lowest level since the financial crisis as investors are braced for the fallout of the first US interest rate rise in nearly a decade.

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

The awards returned Ms. Lawrence, a winner last year for Russell's 'Silver Linings Playbook,' to the stage for an acceptance speech-something she said was no easier a year later.
The U.S. Veterans Day holiday also coincides with other World War One-era holidays around the world, including Remembrance Day in Britain and the Commonwealth nations of Australia and Canada.

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

adv. 绝对地,完全地;独立地

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
From the themed collection: 红星美凯龙构建家居流通4.0体系
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

For over two decades I have been writing about the rise of Asia and the dynamic driving it. There is an extraordinary consensus among east Asian leaders that Asia needs to use this window of opportunity to focus on economic development and growth. War is the biggest obstacle to development. If Asians were truly stupid, they would engage in such wars and derail their enormous development promise. Most Asian leaders, barring North Korea, understand well the dangers of war. Hence, while there will be tensions and rivalries in the region, there will be no wars in the region, in 2014 or in 2015. As 2015 unfolds, I would like to encourage all western pundits to understand the underlying Asian dynamic on its own terms, and not on the basis of western preconceptions.

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

不像这篇文章中其他的人造物品,人工胰腺并不处于前期研究阶段,这个装置确实存在,而且在今年9月份得到了FDA的销售许可
The media mogul is accused of blacklisting the actress after the meeting as well as deploying former Mossad agents to follow her and steal her memoir's manuscript.
global
此外,今年有66位40岁以下的富豪入选,创下了该榜单的记录,诺依曼,希伯尔曼和夏普三人位列其中。

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

sc=scene(n 风景),roll(n 卷)-卷着风景的画卷
妮妮·切利(Neneh Cherry),《空白计划》(Blank Project), Smalltown Supersound
周二,萨尔州成为德国第一个禁止外国政客拉票的地区。德国数个地方议会基于消防安全等技术原因,取消了土耳其部长们原计划的拉票集会。
A meditation on love, loss and the meaning of life. Dog people and Lou Reed fans will be especially susceptible (I plead guilty on both counts), but anyone who ever had a heart is likely to succumb to Ms. Anderson’s ethereal wisdom and her fierce formal wit.

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

It is based on a survey of business schools and another of their alumni who graduated in 2013.
狄更斯在《双城记》中描写法国大革命时,距离事件发生已有近一个世纪。而我则是在今年12月就回顾盘点这一年。因此,我在此描述的某些趋势,可能将在可预见的未来继续存在,而另一些趋势则可能已经开始减弱。作为当今时代“最哗众取宠的权威人士”之一,我只要求各位在阅读这篇评论文章时记住一点:过去的业绩并不能保证将来的表现。

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

民主党能在中期选举中重新夺回美国众议院多数党地位吗?
The clip, taken on a mobile phone, starts with the crowd singing the Frankie Valli lyrics: You're just too good to be true, can't take my eyes off of you'.
经济学家表示,香港住宅市场和商业地产市场都将受到一些相同因素的损害:中国增长放缓、人民币贬值、中国内地反腐以及美国低利率环境将走向终结的预期。然而,住宅市场的发展还受到一个额外因素的阻碍,即2012年政府为减少香港房地产市场上的投机活动而出台的“降温”措施。
The best of 2015
4.Virtual Assistant: 17.6 percent increase

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

The increase of these and other gases from human activity has caused the planet to warm by about 1.5 degrees Fahrenheit since the preindustrial era, which is causing land ice to melt all over the world. The oceans are rising at what appears to be an accelerating pace, and heat waves and torrential rains are intensifying.
这个领域的创新速度非常快。自从Fitbit于2008年成立以来,各家公司已经发布了五到六个完全不同的产品。三星(Samsung)则在九个月内发布了可穿戴设备Galaxy Gear的三到四个衍生产品。索尼(Sony)、Pebble、谷歌和Facebook的头戴式虚拟现实设备Oculus Rift也紧随其后。
A Method to the Madness

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

We learned about the causes and consequences of rising obesity around the world.
WHAT: A house with three bedrooms, two full bathrooms and two half-bathrooms

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

The website claims that "the more you sip, the smarter you (and the bottle) get," but in reality the more you sip, the drunker you get and the less information you'll retain.
结果那些要求进行设身处地和角色扮演的人在随后的提问环节表现最好。准确地说,这些运用设身处地法进行记忆的人记单词的效率是使用其他记忆方式的人的三倍。虽然主持这项实验的科学家们研究的是设身处地法对患有记忆力损伤的人恢复记忆的影响,但无论人们有没有记忆损伤,皆可能受益于此。如果你想记住朋友在哪买了一双鞋子,不妨就试着想象走进店里买鞋的是自己。
另外一件性玩具则显然属于中国皇室。

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

But the change in Wall Street’s — and Silicon Valley’s — appreciation of Mr Cook is down to more than just the 70m iPhones Apple is expected to sell this quarter or the $42bn in sales generated in the previous.
If Dwyane Wade lost 30 pounds of muscle, you wouldn't be able to tell him apart from the high school version of himself.
31岁的罗西每天的工作就是计算五角大楼在养老、医疗和教育福利方面未来的成本。但他说,这份工作不仅仅是鼓捣电子表格数据。他还要与其它政府部门进行沟通,并就金融模型与同事举行头脑风暴会议。

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
From the themed collection: 11月融资规模超千亿 房企分化加剧
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

为什么小皇帝詹姆斯不在双头肌和肩膀上再带那些奇怪的饰物,对此我很好奇。当然,我敢打赌他不会再带那些东西——因为它们没啥用处。

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

在去年的调查中,绝大多数经济学家预期欧洲央行将发起全面量化宽松政策,而今年33个受访者中有几乎快一半的人认为欧洲央行将按兵不动。其他人表示,欧洲央行将扩大量化宽松或下调利率,尽管在那些预期会有更多宽松措施的人中,一部分人强调这家央行不太可能从根本上重塑其现有的政策回应。

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

[?'fekn]
去年上海浦东国际机场通报的准点率最低,该机场仅有52.4%的航班准时起飞,平均延误时长为48分钟。

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
From the themed collection: 2019年房地产市场或将整体平稳
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

报告称,2016年共有6.95亿网民使用手机上网,增长率已经连续第三年超过10%。在所有网民中,用智能手机上网的人占比达到了95.1%,而2015年时这一比例还只有90.1%。
虽然也有各种各样的政策鼓励,但许多会采取减免税务、低息贷款或退税的形式。因此,楼盘运营方或许将不得不从估价中征税,或增加维护费,以此打平楼盘运营的初始成本。“你会遇到没人为你提供前期资金的问题,”卢森堡说。
Sonneborn says he's been dismayed not only by what he sees as Trump's troubling decisions and juvenile moments but also by the president's response after a counterprotester was killed during the August white nationalist rally in Charlottesville, Virginia — which is what cemented Sonneborn's decision to seek office.
有趣的是,“真诚的问候”(unfeigned regards)又重回我们的视野——人们现在可以在印度服务中心的邮件上见到这一18世纪末的流行语。而更胜一筹的是这个签名,一个周五我收到了一则消息,末尾处写到:“周末好”(weekend well)。我差点将最佳名词使动用法奖也颁给它,不料最后一刻却杀出一匹黑马,一位顾问无意中说了句:“我们能把那件事冷毛巾一下吗?”(Can we cold towel that?)

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

根据迪拜政府的最新预测,在迪拜旅游的游客今年将消费313亿美元,远远超过伦敦游客消费的198亿美元。伦敦在游客消费榜单中排名第二。
“学会让经济指标和人民主观的幸福感同步发展是很重要的,因为我们应该不仅仅是追求更强的经济能力,而应追求提高各个领域生活质量。”报告总结道。

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

6.You Spend Time Looking For Other Jobs
Any decision by China’s policymakers to begin selling down the country’s huge reserves would have a large impact on markets.

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

Yan Pu, head of portfolio review in Asia at Vanguard, suspects the Asian product mix may be holding things back. For example, Asian providers offer plenty of equity ETFs but very few fixed income products. In the US, she notes, fixed income ETFs are growing rapidly.

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

In fact, academic research suggests that other economic and social transformations unfolding at the same time have led many people to anchor themselves more fully in their whiteness — even as whiteness itself has lost currency.
准备接收附近酒吧发布的微博广告吧
虽然唐尼主演的几部电影将在明年上映,但规模成本要比他的超级英雄电影小得多。直到2015年《复仇者联盟:奥创纪元》(Avengers: Age of Ultron)上映,他才能迎来下一个丰收季。
时间:2009-10-22 编辑:vicki

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

shatter
上海实施新措施一年以来,受理外籍人士及其家属永久居留申请同比增长6倍。

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

10. Neuroscientists have discovered a whole new role for the brain's cerebellum. It's long been assumed that the cerebellum functions largely outside the realm of conscious awareness, coordinating basic physical activities like standing and breathing, but it could actually play a key role in shaping human behaviour.
英国整体排名第三。“强国”排名第四,“文化影响力”排名第五。
这并不是讽刺小品,这是事实。

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

这个排行榜是不断变化的全球商业环境的年度快照。美国仍然是拥有最多数量的全球2000强公司的国家:总共564家。尽管今年日本失去的成员最多(26家),仍然尾随美国,总计拥有225家公司。
这是两部后自语核(post-mumblecore)喜剧,讲述自我认知及其边界的故事。布西内斯克的影片是完美的怪人三角,三条边分别是盖·皮尔斯(Guy Pearce)、寇碧·史莫德斯(Cobie Smulders)和凯文·科利根(Kevin Corrigan),以德克萨斯州奥斯汀怪人们轻松胡混的伪装出现。皮文的影片探索精神病以及日间电视节目的的黑暗疆域。由于克里斯汀·韦格(Kristen Wiig)的精彩演出(她饰演一个名叫爱丽丝·克里格的彩票得主),《欢迎来到我的世界》成了关于美国梦想者的精彩肖像,既令人不安,也鼓舞人心。
Thus it's rather a shock when you first encounter Nick D'Aloisio striding into London's Bar Boulud restaurant, firmly shaking hands and proceeding to outline his entrepreneurial vision. To imagine him in person, picture a Silicon Valley CEO blessed with an easy manner and 97th percentile media skills. Picture a guy who can confidently expound (while maintaining steady eye contact) on topics ranging from Noam Chomsky's theories to the science of neural networks to the immigrant mind-set to the Buddhist concept of jnana. And now picture this fellow trapped inside the gangly body of a British teen who might easily be mistaken for a member of the pop boy band One Direction-clad in a hipster T-shirt beneath a fitted blazer, hair swooping over his forehead, taking bites of a cheeseburger between bold pronouncements.

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

The standout is "Him," a tear-jerker about queer love and cultural intolerance that, in its understated way, is an LGBTQ civil rights anthem.
James Bond 23 may still be quite a ways away from actually happening, as star Daniel Craig is commited to three chapters in the Millennium Trilogy, starting with the currently in-production The Girl with the Dragon Tattoo. There is currently no talk of hiring someone else to play James Bond, but if Craig is to reprise the role a third time, we still won't see James Bond 23 until 2014 at the earliest.

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
From the themed collection: 广东保障城市停车场建设用地
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

达奇斯说:星巴克在社交方面总是排名前列,2012年也不例外。公司通过社交在2012年赢得了1900万新的粉丝,它针对用户在家和出门的产品也成为用户津津乐道的谈资。
关于7月9日的枪击案,调查人员已逮捕两名年轻人,其中一名18岁。
那么2015年最好的职业是什么?保险精算师高居榜首,他们是分析财务风险方面的专业人员。

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

“有个人在会议中途冲了出去,一句话也没留。”
收入最高的十位模特中有九位都在内衣品牌维多利亚的秘密有相应的工作,大码模特阿什莉是唯一的例外。

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

Hangzhou in Zhejiang Province and Shenzhen in Guangdong Province made the biggest progress in improving traffic with measures including vehicle restrictions and better road links, said the report.
2016年上榜的全球十亿美元级富豪共计1810名,位居次席的是Zara创始人阿曼西奥·奥特加,商界巨擘沃伦·巴菲特紧随其后,埃卢则是位居本榜单的第四名。
据英国《卫报》报道,在去年的伦敦时装周期间,有250名反皮草抗议者,2月份的玛丽卡特兰佐秀场也受到了抗议者激烈的抵制。

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

Costco CEO Craig Jelinek

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
From the themed collection: 8月 楼市进入深度博弈期
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

北京某投资公司总经理汪杰表示,金融和地产业高管较高的薪酬反映出我国发展不平衡的问题。
But researchers this year came up with a new method that makes flexible, realistic ears out of real cells. Those cells come from rats and cows, and they form a collagen gel that can take the shape of any mold. When placed in a mold of a human ear—a mold assembled using a 3-D printer—the gel forms an ear in less than an hour. The artificial ear then just needs a few days growing in nutrients before it's ready to be implanted in a subject.

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

北弗罗里达大学的一个有趣的实验证明光脚跑步比穿鞋跑步更能提高记忆力。和那些在实验室和室内坐在桌子边进行的试验不同,在这个实验中,研究人员们引入了一些有趣的观点来探索提高记忆力的奥秘。实验的研究对象为“工作记忆”,即人们加工信息和回顾生活细节的能力。科学家们发现,光脚跑步比起穿鞋跑步来说,可以对记忆力产生轻微的提高。在试验中,年龄为18-44周岁的参与者们被要求跑两轮,一次穿鞋,一次不穿鞋。
今年夏季,美国ETF管理的资产规模跨过3万亿美元大关,亚太ETF行业管理的资产仅成功爬上3500亿美元关口。

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
From the themed collection: 实木家具究竟环不环保?
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

Aoki-san is a pleasure to work withon storyboard. With Aoki-san on the team it feels like a sure thing. The visionof these animations will be perfect.
['s?ul]

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

但是通常你可以选择匿名求职,Fos说,或者要么就拒绝那个选项坚持在领英上面发布,她补充道这样至少更易被招聘者和经理发现。
9.Yeah, I was a badass on my high school football team! – Because I want to be seen by others in an even stronger light than I see myself。

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

Meme-sharing Facebook groups have become a new college tradition, Mic reported last week, with students across the country trading inside jokes and fighting battles with rival universities via screenshot and caption.

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

宏伟壮丽的教堂、随处可见的博物馆、日益丰富的现代艺术以及伴随夏季节日到来而热情洋溢的大街小巷等,该城市总能带给你意想不到的惊喜和兴奋。
菲律宾参议院一委员会就国内发生的法外处决事件举行了听证会,罗纳德?德拉罗萨(Ronald Dela Rosa)在会上表示,自7月1日杜特尔特就任总统后,有712人在警方缉毒行动中被杀,还有1067起死亡正被作为与毒品相关的自告奋勇者杀人案件在调查中。
以下是根据官方数据(所有收入均按市场汇率折合成了美元)得出的世界主要国家领导人收入排行。
Elspeth Cheung, head of BrandZ valuation at Millward Brown, says: “The top 10 used to be dominated by consumer goods. This year, it’s technology.”

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

Statistics show global research and development expenditure grew at an annual pace of approximately seven percent before 2009, but slowed down to four percent in 2014

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

2015年,全球范围发起的233起反倾销案件中,针对金属行业的案件占比达创纪录的46%,几乎全部是针对钢铁行业的案件。
This year's juries were chaired by AFI board of trustees vice chairs Tom Pollock (for film) and Richard Frank (for TV). Other jury members included Judd Apatow, Halle Berry, Jamie Lee Curtis, Leonard Maltin, authors and scholars representing prestigious universities with recognized motion picture arts and TV programs and film and TV critics from media outlets like NPR, Rolling Stone, TV Guide and The Washington Post.
5.布莱恩·克兰斯顿曾是杀人嫌疑犯

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
From the themed collection: 投资房地产信托不能单纯信抵押物
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

5.谷歌网站管理员工具
After weeks of rumors, Phil Jackson failed to move Carmelo Anthony and Derrick Rose, two players who absolutely should have been traded for the long-term benefit of the franchise.

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

眼下,这位大摩新掌门或许意识到了来自零售经纪业务的微薄盈利还不够华尔街薪酬的血盆大口塞牙缝。预计戈尔曼会决定最终要向交易商高盛(Goldman Sachs)看齐。
We’ve all had them: bosses and managers who make our work lives terrible and couldn’t manage a stack of paper clips, let alone a team of employees. I’ve written about the traits that make for bad bosses before, and in that article, a thoughtful commenter came up with his own list of what makes a good boss。

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

HOW MUCH: $2,050,000

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

'He does smoke cigarettes, he smokes many, many cigarettes.
Despite the fact that each market rebound ended up as a V-shaped affair, each successive rally was carried out with less and less individual stock participation. Glaring divergences between winners and losers, large caps and small caps, preoccupied the commentariat for most of the spring and summer. Deflationary concerns from Europe and the Japanese technical recession further confounded analysts, as Treasury yields and inflation indicators in the U.S. were driven lower despite the improving domestic economy.
单词institute 联想记忆:

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

In a sign that civil service jobs may be losing their appeal, a report issued by recruitment website Zhaopin in late March said more than 10,000 public sector employees, including civil servants and staff members at public institutions, had submitted their resumes to potential employers through the site in just two months. The number was 34 percent higher during the same period last year, the report said.
The world's first flying bicycle flew on November 9, 1961, when Derek Pigott of the University of Southampton flew in a bicycle with an airplane-like body. It was called the Southampton University Man Powered Aircraft (sumpac). Derek furiously pedaled the air-bike to get it off the ground. It then flew 1.8 meters (about 6 ft) above the ground over a distance of 64 meters (210 ft). While the flight was short and slow, it still does not change the fact that it was the first bicycle to fly and at the same time, the first human-powered flight.
Graduates in economics and finance still have great prospects for making big money, the National Business Daily reported, citing a new survey. The average monthly salary for graduates from five major Chinese universities in finance and economics stayed above 10,000 yuan.
the Dutch lender that is a leading financier to farmers and agribusinesses around the world.

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

7. “The Kindergarten Teacher” In his tough, weird knockout, the Israeli director Nadav Lapid spins the story of a teacher’s obsession with a child poet to create a savage portrait of fanaticism and its costs.
invigorate

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

项目长度:19个月
This story pulls directly from the real Bling Ring gang , whose burglaries racked up $3 million over the span of ten months in 2008. All of the celebrities listed in the movie were real victims of this group, who claim to have been motivated by the "cultural obsession" surrounding celebrities' personal lives. Whatever their motives, the Bling Ring is a good reminder to take a step back from the media every once in a while.
It even featured in the March 19, 1870, issue of Scientific American magazine. Made by Thomas Luders from Olney, Illinois, and called a "pedespeed," the wheels then were much smaller, measuring around 36 centimeters (15 in) in diameter. Luders also said the skates could be used by anybody, irrespective of their physique. He himself was a large, heavy man, and he claimed he could use them for two straight hours without getting tired. Another version of wheel skates, appearing in 1923, had its tires on the inside of the foot rather than outside. (Other than the size of the wheels, the main improvement made by Chariot Skates is the small tire at the back of the bigger tire for increased stability.)

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
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About this collection

2015年FT/麦肯锡最佳商业图书奖(2015 Financial Times and McKinsey Business Book of the Year)的获奖作品是《机器人的崛起:大规模失业的威胁与科技》(The Rise of the Robots: Technology and the Threat of Mass Unemployment),这本书对工作自动化的未来做出了令人不安和常常令人消沉的分析。
汉达·阿亚里(Henda Ayari)

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